Pharmaceutical API CAS 55297-96-6 Tiamulin Hydrogen Fumarate USP for Veterinary

• Varieties: General Disease Prevention Medicine
• Component: Chemical Synthetic Drugs
• Type: Antibiotic
• Pharmacodynamic Influential Factors: Animal Species
• Storage Method: Light Proof
• Veterinary Reg. No.: N/a
• Model NO.: API
• Sample: Yes
• GMP: Yes
• ISO: Yes
• Shelf Life: 5 Years
• Transport Package: 25kg/Drum
• Specification: 1kg, 25kg
• Trademark: Veyong
• Origin: China
• HS Code: 2932209090
• Production Capacity: 500000kg/Month

Product Description

CAS number:55297-96-6
Tiamulin hydrogen fumarate is a derivative of pleuromutilin, can be used in veterinary medicine particularly for pigs and poultry.It is a diterpene antimicrobial with a pleuromutilin chemical structure similar to that of valnemulin.
Tiamulin hydrogen fumarate is white or almost white crystalline powder, odorless and tasteless. It is easily soluble in methanol or ethanol, soluble in water, slightly soluble in acetone, and almost insoluble in hexane . 
This product is a bacteriostatic antibiotic, but it also has bactericidal effect on sensitive bacteria at very high concentration. The antibacterial mechanism of action is to inhibit bacterial protein synthesis by binding to the 50s subunit of the bacterial ribosome.
Tiamulin hydrogen fumarate has good antibacterial activity against a variety of Gram-positive cocci, including most staphylococci and streptococci (except group D streptococci) and a variety of mycoplasmas and some spirochetes. However, the antibacterial activity against some negative bacteria is very weak, except for Haemophilus species and some E. coli and Klebsiella strains.
Tiamulin hydrogen fumarate is easy to be absorbed after oral administration in pigs. About 85% of a single dose is absorbed, and peak concentrations occur in 2 to 4 hours. It is widely distributed in the body, with the highest concentration in the lungs. Tiamulin hydrogen fumarate is metabolized in the body into 20 metabolites, some with antibacterial tranquility. About 30% of the metabolites are excreted in the urine and the remainder is excreted in the feces.
Usage:Tiamulin hydrogen fumarate is used for the treatment of swine pneumonia caused by Actinobacillus pleuropneumoniae and swine blood dysentery caused by Treponema hyodysenteriae. As a feed drug additive for pigs can promote weight gain. It is also effective against chronic respiratory disease in chickens, mycoplasma hyopneumonia, and staphylococcal synovitis in chickens.
Content:≥ 98%
Packing: 25kg/cardboard drum
Preparations: 10%, 45% 80% Tiamulin hydrogen fumarate premix / soluble powder

Specification	EP; USP	Usage	Antibiotic
Raw Material	Tiamulin Hydrogen Fumarate	Species	Cattle, sheep, swine, camel,chicken
Dosage Form	Powder	Sample	Yes
Packing	25kg/bag/drum	Delivery Time	3days
MOQ	100kg	Payment Term	T/T, D/P, D/A, L/C
GMP	Yes	ISO9001	Yes
FDA	Yes	COS	Yes