Best Price for Spinosad, Spinosad API, Public Health, Agro,

• Varieties: Parasite Disease Prevention Medicine
• Component: Chemical Synthetic Drugs
• Type: The First Class
• Pharmacodynamic Influential Factors: Incompatibility
• Storage Method: Prevent High or LowTemperature
• Transport Package: 25kg/Bag/Drum
• Specification: 95%
• Trademark: Veyong
• Origin: China
• Production Capacity: 1000mt

Product Description

 

SPINOSAD Basic information

Product Name:	SPINOSAD
Synonyms:	SPINOSAD;(2r-(2r*,3as*,5ar*,5bs*,9s*,13s*(2r*,5s*,6r*),14r*,16as*,16br*))-ethyl;)oxy)-13-((5-dimethylamino)tetrahydro-6-methyl-2h-pyran-2-yl)oxy)-9-ethyl-14-m;Spinosad A;Spinosyn A Solution, 1000ppm;1H-As-indaceno(3,2-D)oxacyclododecin-7,15-dione, 2-((6-deoxy-2,3,4-tri-o-methyl-alpha-L-mannopyranosyl)oxy)-13-(((2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl)oxy)-9-ethyl-2,3,3A,5A,5B,6,9,10,11,12,13,14,16A,16B-tetradecahydro-14-methyl-, (2R,3as,5ar,5bs,9S,13S,14R,16as,16br)-;1H-As-indaceno(3,2-D)oxacyclododecin-7,15-dione, 2,3,3A,5A,5B,6,9,10,11,12,13,14,16A,16B-tetradecahydro-2-((6-deoxy-2,3,4-tri-o-methyl-alpha-L-mannopyranosyl)oxy)- 13-((5-dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl)oxy)-9-ethyl-14-methyl-, (2R-(2R*,3as*,5ar*,5bs*,9S*,13S*(2R*,5S*,6R*),14R*,16as*,16br*))-;Ccris 8937
CAS:	131929-60-7
MF:	C41H65NO10
MW:	731.96
EINECS:	620-162-1
Product Categories:
Mol File:	131929-60-7.mol

SPINOSAD Chemical Properties

Boiling point	801.5±65.0 °C(Predicted)
density	1.16±0.1 g/cm3(Predicted)
vapor pressure	Spinosyn A: 3.2 x 10^-8 Pa Spinosyn D: 2.1 x 10^-8 Pa
Water Solubility	Spinosyn A: 290 mg l^-1 (pH 5); Spinosyn D: 29 mg l^-1 (pH 5)
pka	Spinosyn A: 8.1 (base); Spinosyn D: 7.8 (base)
EPA Substance Registry System	Spinosyn A (131929-60-7)

Safety Information

RIDADR	3077
HazardClass	9
PackingGroup	III
Hazardous Substances Data	131929-60-7(Hazardous Substances Data)

MSDS Information

 

SPINOSAD Usage And Synthesis

Uses	Spinosyn A is the major component of a complex of unusual, hydrophobic macrocyclic lactones isolated from Saccharopolyspora spinosa in 1991. The 12-membered macrocyclic lactone is fused to form a rare 12-5-6-5 tetracyclic ring system, with the macrocycle and the terminal cyclopentane bearing glycosides. Spinosyn A is a potent insecticide for crop pathogens and ectoparasite control on animals. The spinosyns have a unique mechanism of action involving disruption of nicotinic acetylcholine receptors.
Definition	ChEBI: A spinosyn in which the sugar amino and hydroxy groups are globally methylated. One of the two active ingredients of spinosad.
Veterinary Drugs and Treatments	For the prevention and treatment of fleas for one month on dogs 14 weeks of age and older. Spinosad is a group 5 nicotinic acetylcholine receptor agonist, that causes involuntary muscle contractions and tremors secondary to motor neuron activation. Prolonged exposure causes paralysis and flea death. Flea death begins within 30 minutes of dosing and in 4 hours is complete. Spinosad does not interact with bindings sites of other insecticidal agents (GABA-ergic or nicotinic).
Metabolic pathway	Spinosad consists of two major components, namely psinosyns A (ca 85%) and D (ca 15%). When either 14C-spinosyn A or -spinosyn D is applied in the soil under aerobic conditions, the major degradation product of spinosyn A is spinosyn B, resulting from demethylation on the forosamine sugar. Other degradation products are hydroxylation products of psinosyns A and B, probably on the aglycone portion of the molecule.
Degradation	Spinosad is relatively stable in water with no observed decomposition between pH 5 and 7. Measured DT50 values at pH 9 were 200 and 259 days, respectively, for spinosyns A and D (Saunders and Bret, 1997). Aqueous photolysis was very rapid with a DT50 of < 1 day in pH 7 buffered water at 25 °C (DowElanco, 1996). Spinosad was rapidly dissipated and degraded in an outdoor mesocosm study and on plant surfaces (Saunders and Bret, 1997).
Toxicity evaluation	Acute oral LD50 for rats: 2,000-5,000 mg/kg

SPINOSAD Preparation Products And Raw materials

Raw materials

D(+)-Glucose-->SOYBEAN OIL-->Dextrin-->Soy bean Isoflavone Isoflavone 10-40%-->Maltose-->CATION STANDARD - SODIUM-->D(+)-Xylose-->D-Mannitol-->Peptone-->5 KG YEAST EXTRACT SERVABACTERPOWDER-->MILK-->Meat extracts, beef-->Methyl Oleate-->D-GALACTOSE 1-[2-(2-AZIDOETHOXY)ETHOXYETHYL]-2,3,4,6-TETRA-O-ACETATE-->SOYBEAN MEAL-->beta-D-Fructopyranose-->D-Ribose-->ANION STANDARD - NITRATE-->Raffinose-->N-Z-AMINE A-->SPINOSAD

Company Profile

Hebei Veyong pharmaceutical Co., Ltd, was established in 2002, located in Shijiazhuang City, Hebei Province, China, next to the Capital Beijing. She is a large GMP-certified veterinary drug enterprise, with R&D, production and sales of veterinary APIs, preparations, premixed feeds and feed additives. As Provincial Technical Center, Veyong has established an innovated R&D system for new veterinary drug, and is the nationally known technological innovation-based veterinary enterprise, there are 65 technical professionals. Veyong has two production bases: Shijiazhuang and Ordos, of which the Shijiazhuang base covers an area of 78,706 m2, with 13 API products including Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, and 12 preparation production lines including injection, oral solution, powder, premix, bolus, pesticides and disinfectant, ects. Veyong provides APIs, more than 100 own-label preparations, and OEM & ODM service.
Veyong attaches great importance to the management of EHS(Environment, Health& Safety) system, and obtained the ISO14001 and OHSAS18001 certificates. Veyong has been listed in the strategic emerging industrial enterprises in Hebei Province and can ensure the continuous supply of products.
Veyong established the complete quality management system, obtained the ISO9001 certificate, China GMP certificate, Australia APVMA GMP certificate, Ethiopia GMP certificate, Ivermectin CEP certificate, and passed US FDA inspection. Veyong has professional team of registeration, sales and technical service, our company has gained reliance and support from numerous customers by excellent product quality, high-quality pre-sales and after-sales service, serious and scientific managemen. Veyong has made long term cooperation with many internationally known animal pharmaceutical enterprises with products exported to the Europe, South America, Middle East, Africa, Asia, etc. more than 60 countries and regions. 
 Veyong takes "Maintain animal health, improve quality of life" as the mission, strives to become the most valuable veterinary drug brand, and looks forward to active cooperation with global customers.
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FAQ

1. who are we?
   We are based in Hebei, China, start from 2002, sell to more than 60 countries or regions. There are total about 400 people in our company.
2. how can we guarantee quality?
   We have established the complete quality management system, obtained the ISO 9001 certificate, GMP certificate, Australia APVMA GMP certificate, Ethiopia GMP certificate, Ivermectin CEP certificate and US FDA. All products would pass the inspection by the Quality Department before releasing.
3. what can you buy from us?
   We could supply 13 API products (Ivermectin, Eprinomectin, Tiamulin Hydrogen Fumarate, Abamectin, Oxytetracycline HCL, Tilmicosin, Tilmicosin Phosphate, Florfenicol, Doxycycline HCL, Tylvalosin Tartrate, Tildipirosin, Valnemulin HCL), and 12 dosage forms including injection, oral solution, powder, premix, pulvis, granule, bolus/tablet, pouring on solution, injectable powder, pesticides and disinfectant, ects.
4. why should you buy from us not from other suppliers?
   Veyong is established in 2002,with an intent of providing affordable and high quality veterinary formulations for all species of animals.
5.  what services can we provide?
   Accepted Delivery Terms: EXW,FOB,CFR,CIF;
   Accepted Payment Currency:USD,EUR,CNY;
   Accepted Payment Type: T/T,D/A,D/P, L/C;