Composition:
Each bolus contains oxytetracycline hydrocloride 100mg
Pharmacological action:
Oxytetracycline is a tetracycline broad-spectrum antibiotic, which has a strong effect on gram-positive bacteria such as Staphylococcus, Streptococcus hemolyticus, Bacillus anthracis, Clostridium tetani and Clostridium, but not as good as lanlactams . It is more sensitive to Gram-negative bacteria such as Escherichia coli, Salmonella, Brucella and Pasteurella, but not as good as aminoglycoside and amide alcohol antibiotics. This product is opposite Kettsiae, chlamydia, mycoplasma, spirochetes, actinomycetes and certain protozoa also have inhibitory effects.
Pharmacokinetics:
Oral absorption of oxytetracycline is irregular and incomplete. It is easily absorbed by hungry animals. The bioavailability is 60%~80%. It is mainly absorbed in the upper part of the small intestine. Multivalent metal ions such as magnesium, aluminum, iron, zinc, and manganese in the gastrointestinal tract form insoluble chelates with this product, which reduces drug absorption. The plasma concentration reaches its peak 2 to 4 hours after oral administration. After being absorbed, it is widely distributed in the body and easily penetrates into the chest, abdominal cavity and breast milk. It can also enter the fetal circulation through the placental barrier, but the concentration in the cerebrospinal fluid is low. Oxytetracycline is mainly filtered and excreted by the glomerulus in its original form.
Indications:
For the treatment of Gram-positive, negative bacteria and mycoplasma infections.Oxytetracycline tablet can be used to treat calf pullorum, lamb diarrhea, piglet yellow diarrhea and pullorum, chick pullorum caused by Escherichia coli or Salmonella; bovine hemorrhagic sepsis caused by Pasteurella multocida, swine pneumonia and fowl cholera, etc.; Mycoplasma Caused by bovine pneumonia, swine asthma and chicken chronic respiratory disease. It also has a certain curative effect on Tyler's disease, actinomycosis, and leptospirosis caused by blood spores.
Dosage & Administration:
Oral Administration.
For calves, sheep, and goat: 10mg-25mg per kg body weight.
For chickens and turkeys: 25-50mg per kg body weight.
2-3 times daily, for 3 to 5 days.
Withdrawal Period:
Calves: 7 days.
Poultry: 4 days.
Precaution:
Not for use in poultry producing eggs for human consumption.
Storage:
Store at room temperature and protect from light.
Keep out of the reach of children.
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